
A steady large-cap risk-flagged situation trading at a premium valuation.
Mkt Cap
$29.38B
P/E
—
PEG
3.94
P/B
1.57
Dividend
—
ROE
7.7%
About the business
Biogen Inc. discovers, develops, manufactures, and delivers therapies in the United States, Europe, Germany, Asia, and internationally. The company provides TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, and TYSABRI for multiple sclerosis (MS); SPINRAZA for spinal muscular atrophy; SKYCLARYS to treat Friedreich's Ataxia; QALSODY for treating amyotrophic lateral sclerosis; FUMADERM to treat plaque psoriasis; BENEPALI, an etanercept biosimilar referencing ENBREL; IMRALDI, an adalimumab biosimilar referencing HUMIRA; FLIXABI, an infliximab biosimilar referencing REMICADE. It offers LEQEMBI for the treatment of Alzheimer's disease; ZURZUVAE for the treatment of postpartum depression; RITUXAN to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; OCREVUS for relapsing MS and primary progressive MS; LUNSUMIO to treat relapsed or refractory follicular lymphoma; glofitamab for aRelapsed or refractory diffuse large B-cell lymphoma; and other anti-CD20 therapies. Biogen Inc. has collaboration and license agreements with Merz Therapeutics; Alkermes Pharma Ireland Limited; Denali Therapeutics Inc.; UCB; Eisai Co., Ltd.; Genentech, Inc.; Neurimmune SubOne AG; Ionis Pharmaceuticals, Inc.; Samsung Bioepis; and Sage Therapeutics, Inc., as well as collaborations with Stoke Therapeutics, Inc. for the development and commercialization of zorevunersen, a disease modifying medicine for the treatment of Dravet syndrome; Dayra Therapeutics, Inc. to develop oral macrocyclic peptides; Vanqua Bio, Inc. for developing Vanqua's preclinical oral C5aR1 antagonist compound; City Therapeutics, Inc. to develop select novel RNAi therapies; and ALTEOGEN Inc. to develop subcutaneous (SC) formulations of biologics utilizing ALT-B4. The company was founded in 1978 and is headquartered in Cambridge, Massachusetts.
Who would buy BIIB?
Consensus 27/100 · Aligned · Investors mostly agree.
Endorses
· 2 frameworksDebt/Equity < 0.5 0.35 clears "< 0.50".
Payout Ratio < 70% 0.0% clears "< 70.0%".
Rejects
· 3 frameworksBuying is limited to a single filer (MURPHY NICOLE, $585). Single-insider buys are worth noting but carry less weight than broad-based conviction — they can reflect an outlier view rather than a shared read inside the C-suite. Over the 6M window, insiders are net buyers by 84,208 shares.
In Prism's context
Insider activity is inconclusive here. The stock's case should lean on the framework verdict (Fails criteria, score 27/100) and the archetype read (Risk-First).
| Insider | Role | Type | Date | Shares | Avg price | Value | Own |
|---|---|---|---|---|---|---|---|
| KEENEY ADAM JAMES | Officer | Transaction | May 1, 2026 | 939 | — | — | Direct |
| GODBOUT SEAN | Officer | Transaction | Apr 1, 2026 | 181 | — | — | Direct |
| MURPHY NICOLE | Officer | Open-market buy | Feb 12, 2026 | 3 | $195.00 | $585 | Direct |
| SINGHAL PRIYA | Officer | Open-market sell | Feb 9, 2026 | 2,660 | $199.83 | $532K | Direct |
| IZZAR RACHID | Officer | Transaction | Feb 6, 2026 | 6,889 | — | — | Direct |
| MURPHY NICOLE | Officer | Transaction | Feb 6, 2026 | 8,725 | — | — | Direct |
| KEENEY ADAM JAMES | Officer | Transaction | Feb 6, 2026 | 5,080 | — | — | Direct |
| GROGAN JANE | Officer | Transaction | Feb 6, 2026 | 3,258 | — | — | Direct |
| GODBOUT SEAN | Officer | Transaction | Feb 6, 2026 | 1,079 | — | — | Direct |
| ALEXANDER SUSAN H | Officer | Transaction | Feb 6, 2026 | 9,046 | — | — | Direct |
| GREGORY GINGER | Officer | Transaction | Feb 6, 2026 | 7,183 | — | — | Direct |
| KRAMER ROBIN C. | Chief Financial Officer | Transaction | Feb 6, 2026 | 5,003 | — | — | Direct |
| SINGHAL PRIYA | Officer | Transaction | Feb 6, 2026 | 6,900 | — | — | Direct |
| VIEHBACHER CHRISTOPHER | Chief Executive Officer | Transaction | Feb 6, 2026 | 24,461 | — | — | Direct |
| SINGHAL PRIYA | Officer | Open-market sell | Feb 2, 2026 | 748 | $179.30 | $134K | Direct |
| SINGHAL PRIYA | Officer | Transaction | Jan 30, 2026 | 1,829 | — | — | Direct |
| VIEHBACHER CHRISTOPHER | Chief Executive Officer | Transaction | Dec 1, 2025 | 7,040 | — | — | Direct |
Insider activity from Yahoo Finance (quoteSummary: insiderTransactions + netSharePurchaseActivity). Cached 6 hours. · Insiders hold 0.2% of shares outstanding.
Net 6M: +84,208 sh
Price history
Drag across the chart to select a custom period — all analysis below refocuses to that window.
What this means: Price near 52-week highs despite weak framework scores — market enthusiasm is running ahead of the fundamentals most legends look at.
Add Biogen Inc. at a hypothetical weight and Prism recalculates your whole book:
Sharpe, Sortino, volatility, max drawdown, beta — before and after.
How much this shifts your top sector weight and overall diversification.
Whether this leans your book more toward Quality, Value, Growth, Deep Value, Income, or Momentum.
Portfolio analytics are part of the member experience.
Sign in to run this simulationBIIB: 59% estimated probability of outperforming over the next 12M window. 4 of 6 signal families positive (high confidence). Strongest support: Reverse DCF: low expectations bar. Main risk to monitor: Net insider selling ($2.8M).
Probabilistic research output, not financial advice. Prism recommendations are based on available data, historical relationships, and model assumptions. They do not guarantee future returns. Conduct independent due diligence before any investment decision.
Backtested and similar-setup statistics may be affected by survivorship bias, look-ahead bias, overfitting, transaction costs, liquidity constraints, and data limitations. Probability estimates are anchored heuristics — not validated forecasts — until the walk-forward backtest pipeline is in place.
P/B 1.57× · FCF yield 6.5%
3% below fair value
Indicative only. Probabilities are model-implied weights for stress-testing — not forecasts.
A turnaround takes hold: margin recovers toward peer averages, revenue stabilises, and the market re-prices the asset value rather than the running earnings.
No deterioration, no surprise re-acceleration. 23% operating margin and 2% top-line growth chug along; the multiple slowly converges to the central fair-value estimate.
Sector: Healthcare. MENA-aware investors can sanity-check whether the US name is offering value relative to regional peers.
| Metric | BIIB | GCC median | MENA median | Global ex-US |
|---|---|---|---|---|
| P/E (TTM) | — | 24.0× | — | 20.0× |
| P/B | 1.57× | 4.80× | — | 3.80× |
| Dividend yield | — | 1.40% | — | 1.80% |
| ROE | 7.7% |
Reported EPS $3.57 vs $2.02 expected — well outside the normal beat-and-raise band. The market typically rewards a print this size only if it is read as durable, not one-off. Trailing operating margin: 22.9%.
Confirms operating leverage — 31% trailing EPS growth + a beat of this size is the pattern that drives multi-year re-rates.
If ROE (8%) and operating margin (23%) are stable or rising, the beat is consistent with compounding rather than one-off.
Outsized beats on thin trailing quality often invite multiple expansion that doesn't survive the next print.
Next earnings
Thu, Jul 30 · consensus EPS $2.02 · last actual $3.57
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P/E Ratio (TTM)
N/A
PEG Ratio
3.94
P/B Ratio
1.57
EPS Growth
31.1%
Revenue Growth
1.9%
Debt / Equity
0.35
Net Cash / Share
$-15.44
Return on Equity
7.7%
Gross Margin
78.7%
Operating Margin
22.9%
FCF / Share
$12.98
Current Ratio
3.06
ROE > 20% is 7.7% — fails "> 20.0%".
Net Cash Positive (NCAV proxy) is $-15.44 — fails "> $0.00".
ROE > 25% (elite) is 7.7% — fails "> 25.0%".
Roughly fairly valued; valuation is a neutral input.
Returns and margins are healthy and consistent.
Capital structure is conservative and well-covered.
Price action is firm and trending higher.
Informed money is leaning the other way — net selling or thin interest.
Mixed catalyst picture.
Among 105 historical setups with similar Prism Score and signal-agreement profiles, 58% beat the benchmark over the next 12 months, with average excess return of +4.0% / yr.
ROE 8% · Op margin 23%
D/E 0.35 · CR 3.06
2 insiders buying
No tracked superinvestor holds it
Buyback runway via FCF
96% through 52w range
EPS 31% · Rev 2%
Cyclical earnings prove to be at peak; revenue stalls and the multiple, already low, drifts lower as estimates re-rate down.
| — |
| 15.0% |
Institutional Own.
97.6%
Insider Own.
0.2%
Dividend Yield
N/A
Book Value / Share
$126.37